During his preaching journeys, the apostle Paul used several of the famous Roman roads. When he came to Rome as a prisoner he traveled the Appian Way (Latin Via Appia).
There we found brothers and were invited to stay with them for seven days. And so we came to Rome. And the brothers there, when they heard about us, came as far as the Forum of Appius and Three Taverns to meet us. On seeing them, Paul thanked God and took courage. And when we came into Rome, Paul was allowed to stay by himself, with the soldier who guarded him. (Acts 28:14-16 ESV)